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Sedation is typically used for common diagnostic tests that require prolonged immobilization such as magnetic resonance imaging (MRI) and computed axial tomography (CAT) scanning.

Some cases that require sedation may also necessitate the use of analgesics to decrease pain associated with a procedure or test.

A detailed past history, especially prior experiences with sedatives and other anesthetics is an important part of preparatory assessment.

It is important to determine if there were any untoward side effects associated with a previous medication.

An extensive survey of death in 100,000 cases published in 1988 revealed that death within seven days was 2.9 times greater when one or two anesthetic drugs were used than when using three or more medications.

As of 2000 this study is accepted as standard practice and multiple IV anesthetics is the preferable recommendation for optimal patient care.

Patient positioning is important to prevent blood pressure changes or nerve damage associated with abnormal position.

Patients are also monitored for pulse rate, respiration, blood pressure, and temperature.

The major goal for recovery room monitoring is assessment of residual drug effects.Patients receiving conscious sedation are capable of rational responses, and they are able to maintain their airway for ventilation.The hallmark of conscious sedation is that it does not alter respiratory, cardiac, or reflex functions (nerve reflexes from the brain) to the level that requires external support for these vital functions.Because of these additive effects, these medications taken with other sedatives or alcohol (also a sedative hypnotic drug) may increase chances for accidental death.In general, most of the medications that induce sedation may alter breathing and cardiac stability.

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Clinical situations for unconscious sedation typically involve eating and drinking protocols starting the day before the procedure.