Menounos acted in and produced Adventures of Serial Buddies, which is credited with being the first serial killer buddy comedy.
At the age of 17, Menounos produced In the Land of Merry Misfits, an independent film fairy tale.
On August 4, 2011, it was announced that she would join Warner Bros.'s Extra, where she co-hosted the show with Mario Lopez. Drew's Lifechangers, with plans to develop new projects.
From December 17 to 20, 2007, Menounos hosted the reality game show miniseries Clash of the Choirs.
The film premiered at the 2007 Tribeca Film Festival.
for which she was named the 2014 CES Entertainment Matters Ambassador.
In 2006, Menounos appeared in the music video for "A Public Affair" by Jessica Simpson.
On April 27, 2007, Menounos starred in Kickin' It Old Skool.