Consolidating new memories requires the amygdala and
Particular attention is paid to the time windows during which amnestic and other treatments during memory consolidation/reconsolidation are effective.
Similarities and differences between memory consolidation on initial learning and repeated consolidation (reconsolidation) on reactivation by a conditioned stimulus and context are discussed.
It has been assumed that once this occurs, the memory is "fixed" — a permanent, unchanging, representation.
With new techniques, it has indeed become possible to observe these changes (you can see videos here).
There is, however, some evidence that the hippocampus can be involved in older memories — perhaps when they are particularly vivid.
Here we show that consolidation but not reconsolidation of inhibitory avoidance memory requires the expression of the transcription factor CCAAT enhancer binding protein β (C/EBPβ) in the hippocampus.Hypothetical concepts are presented in relation to the possibility of renewing memory on reconsolidation and various pathways of influencing it.Long-term memory formation consists of multiple phases."Consolidation" is a term that is bandied about a lot in recent memory research. Initially, information is thought to be encoded as patterns of neural activity — cells "talking" to each other.Later, the information is coded in more persistent molecular or structural formats (e.g., the formation of new synapses).
The entorhinal cortex, on the other hand, gives evidence of temporally graded changes extending up to 20 years, suggesting that it is this region that participates in memory consolidation over decades.