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After water and other substances leave the surface of the renal tubule, they are reabsorbed by the capillaries, into the bloodstream.

Tubular secretion is the process in which renal tubule extracts chemicals from the capillary's blood and secretes them into the tubular fluid.

Urine formation is a very sophisticated process that takes place in the kidneys.

Kidney disease can sometimes be detected by the presence of protein (especially albumin) or blood in the urine.

It allows them to maintain a relatively stable glomerular filtration rate in spite of changes in arterial blood pressure.

The second stage of urine formation is tubular reabsorption and secretion.

Some substances are retained in the bloodstream because they are bound to plasma proteins that cannot get through the membrane.

For example, most calcium, iron, and thyroid hormone in the blood are bound to plasma proteins that retard their filtration by the kidneys.

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Fluids comprising excess water, salt and metabolic waste products are extracted from the blood as it enters the Glomerular filtration is a process in which water and some other substances in the blood plasma pass from the capillaries of the glomerulus into the Bowman's capsule.

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